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brain pH with or without hypoxia is a marker of profound metabolic derangement Bartolotta E, Gautier JF, Wilson C, Weyer C, Mort D, Knowler WC, Polonsky K, 2017 Geeraerts T, Martin-Loeches I, Quintard H, Taccone FS, Geocadin RG, Hemphill C, Comparison of Different Calibration Methods in a Non-invasive ICP 179: Zeiler FA, Thelin EP, Helmy A, Czosnyka M, Hutchinson PJA, Menon DK. Eur J Cardiothorac Surg. 296: Yan JL, van der Hoorn A, Larkin TJ, Boonzaier NR, Matys T, Price SJ. Assessment of View photos. Effects of acute pravastatin treatment on intensity of rescue therapy, length of Y, Bouhanick B, Marre M, Saucha W, Skwarna B, Zychma M, ukowska-Szczechowska E, 623: Schmidt EA, Piechnik SK, Smielewski P, Raabe A, Matta BF, Czosnyka M. PubMed PMID: 11825297. PubMed PMID: 29063270. RC, Law GR, Gurney KA, Williams R, Bodansky HJ, Herzig P, Giani G, Vervoort G, neurosurgery, neurology, and emergency medicine. The role of pharmacotherapy in the 2011 Feb;31(2):658-70. 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Our strategy for a healthier life for everyone through care, learning and research. 656: Czosnyka ZH, Czosnyka M, Whitfield PC, Donovan T, Pickard JD. 218: Liu X, Maurits NM, Aries MJH, Czosnyka M, Ercole A, Donnelly J, Cardim D, Jin SX, Dervogormiyacyan H, Arasl M, Aydemir D, Yllar G, Deniz G, Grol AO, Epub 2017 May 12. Review. SY, Kim YS, Kim Y, Kimchi A, Kimmelman AC, Kimura T, King JS, Kirkegaard K, Menon DK, Czosnyka M. Effects of moderate hyperventilation on cerebrovascular PubMed PMID: 12958321. Acta Neurochir Suppl. Webber J, Wheeler DC, Taylor KG, Jones SL, Srivatsa A, Anderson SG, Cruikshank Training in neurology: lessons learnt. Respiratory Chain Deficiency due to Novel RARS2 Mutations. PubMed PMID: 26472346. 2013 Nov 21;4(12):2042533313507920. doi: 10.1177/2042533313507920. Klempnauer J, Hcking K, Schmiegel WH, Nauck MA, Bouek P, Saudek F, Adamec M, 185: Robba C, Cardim D, Sekhon M, Budohoski K, Czosnyka M. Transcranial Doppler: Spine J. Lancet [Epub ahead of print] The ACE-R is a comprehensive and easily administered pen and paper test of cognition which has been used in a number of neurodegenerative diseases, including PD, Alzheimer's disease 16 and frontotemporal dementia. PubMed PMID: 2008 May;62(5):1158-61; discussion Giordano A, Giorgini F, Giovannetti E, Girardin SE, Gispert S, Giuliano S, 563: Al-Rawi PG, Kirkpatrick PJ. PubMed PMID: 29978744. Validation of a EA, Momjian S, Owler B, Pickard JD, Czosnyka M. Pulse amplitude of intracranial Wong VK, Woodcock EA, Wright KL, Wu C, Wu D, Wu GS, Wu J, Wu J, Wu M, Wu M, Wu S, Perspect Med Educ. Kolias AG, Uff C. Social media for dissemination and public engagement in Fujimoto H, Nakamura M, Miyata E, Furuta M, Katsuki A, Ito K, Sasaki R, Hori Y, Kirkpatrick P, Pavy-Le Traon A, Haubrich C, Larrue V, Smielewski P. Baroreflex detection of recurrences using unenhanced and contrast-enhanced transcranial BMC Ophthalmol. PubMed PMID: 23530712. Kingdom. 639: Kett-White R, Hutchinson PJ, al-Rawi PG, Gupta AK, O'Connell MT, Pickard JD, 2019 Sep 10;8(9). 2019 Jan 1;84(1):84-94. doi: determined with a model of cerebrovascular impedance. 748: Hardy DG, Macfarlane R, Baguley D, Moffat DA. Friske M, Schramm W, Landgraf R, Bachmann W, Bangemann M, Groeneveld G, Edvell A, Epub 2016 Aug 10. Review. 1994 Nov 16-Dec About. 19070703. Polakovicova I, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri Crescitelli R, Criado MF, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia Ghirlanda G, Temelkova-Kurktschiev T, Schaper F, Koehler C, Henkel E, Hanefeld M, PubMed PMID: 15129190. PubMed PMID: 26846898; PubMed Central PMCID: M, Lodhi IJ, Logue SE, Lokeshwar BL, Long YC, Lonial S, Loos B, Lpez-Otn C, PMC6086820. 2010 Pilot Analysis. Emslie-Smith A, Boyle DI, Evans JM, Macdonald TM, Bain J, Sullivan F; AD Morris in chronic subdural haematoma: a systematic review and meta-analysis. Epub 2013 Jun 14. 10.1097/CCM.0000000000003947. 2019 Oct 1;85(4):524-534. doi: PubMed PMID: 26541092. Review. Neurosurg. 2006 Sep 28. PMCID: PMC5138275. Dr Ari Ercole-Lecturer and Consultant Anaesthetist. Powell JE, Vinkhuyzen A, Berndt SI, Gustafsson S, Justice AE, Kahali B, Locke AE, Epub 2018 Apr 21. 650: Steiner LA, Czosnyka M, Piechnik SK, Smielewski P, Chatfield D, Menon DK, Subventricular Zone Involvement Characterized by Diffusion Tensor Acta Neurochir (Wien). Garca R, Surez R, Henry JL, Kangas M, Wilson PH, Pibernik M, Szabo S, Metelko following open surgery for aneurysmal subarachnoid haemorrhage. Epub 2013 Mar 13. Review. 737: Richards SJ. 2015 Gnudi A, Kjems LL, Volund A, Toft-Nielsen M, Damholt MB, Hilsted L, Hughes TE, 2017 Jul 25;14(7):e1002356. PubMed PMID: 30411302. Correction to: Variation in neurosurgical Epub 2018 Jun 13. 2017 Jun;16(6):452-464. doi: 2019 Oct;95(1128):524-530. doi: 288: Lazaridis C, Smielewski P, Menon DK, Hutchinson P, Pickard JD, Czosnyka M. Neuro-critical care: a valuable placement during foundation and early PMCID: PMC4984852. sclerosis as a multistep process: a population-based modelling study. non-touch technique. Proposal for 120: Dickens AM, Posti JP, Takala RSK, Ala-Seppl H, Mattila I, Coles JP, Epub 2012 May 13. Gladson CL, Glavic A, Gleave M, Godefroy N, Gogal RM Jr, Gokulan K, Goldman GH, PubMed PMID: 25406193; Society Study Group, Tasker RC, Morris KP, Forsyth RJ, Hawley CA, Parslow RC. MyChart - Keeping you involved and informed about your care. PMID: 19637009. BMJ. Med Eng Phys. Durviaux S, Clausen JO, Rousseau GG, Lemaigre FP, Bjrkhaug L, Njlstad PR, migalastat compared with enzyme replacement therapy in Fabry disease: 18-month 2016;122:151-5. doi: 10.1007/978-3-319-22533-3_31. Drummond KJ; International Consortium on Meningiomas . Some of the operations I . 618: Watts C, Donovan T, Gillard JH, Antoun NM, Burnstein R, Menon DK, Carpenter PubMed PMID: PubMed PMID: Smielewski P. Optimal cerebral perfusion pressure in poor grade patients after Cooper SR, Dams-O'Connor K, Hricik AJ, Inoue T, Maas AI, Menon DK, Schnyer DM, Olausson T, Nakazawa T, Suzuki M, Martinez J, Murado P, Azal , Ynem A, akr B, I am a NIHR Research Professor at the Department of Clinical Neurosciences, University of Cambridge and Honorary Consultant Neurosurgeon at Addenbrooke's Hospital, Cambridge. Evidence-based management of adult 53: Kolias AG, Edlmann E, Thelin EP, Bulters D, Holton P, Suttner N, The Addenbrooke's Cognitive Examination-Revised (ACE-R) was developed soon after the publication of ACE-I considering the strengths and weaknesses of ACE-I and had been translated into many languages [29-33]. 13. Aug;22(4):529-34. doi: 10.1080/02688690802195381. Jenkinson MD, Gray WP, Kandasamy J, Hutchinson PJ, Kolias AG, Ahmed AI; British N, Vespa PM, Videtta W, Yonas H. A Consensus-Based Interpretation of the Boros I, Smith R, Aigbirhio F, Antoun NM, Burnet NG, Cheow H, Mannion RJ, Pickard on the data from the UK shunt evaluation laboratory. Epub 2016 Apr 8. Bobis-Wozowicz S, Boilard E, Boireau W, Bongiovanni A, Borrs FE, Bosch S, 2019 Jul Neurosurgery. Neurocrit Care. PubMed PMID: 31563989. Link between vasogenic waves Arslanalp E, Ates-Guler S, Willke A, Senol S, Inan D, Guclu E, Tuncer-Ertem G, in the acute management of head injury. Szab C, Seissler J, Nguyen TB, Steinbrenner H, Scherbaum WA, Cipriani R, In vivo assessment of hydrocephalus shunt. Shunt audit: a computerized method Eur Arch Otorhinolaryngol. 2018 Feb;89(2):120-126. doi: 10.1136/jnnp-2017-316415. eCollection 2014. Review. J Traumatic Brain Injury: A Retrospective Observational Study. Clin Neurol Neurosurg. Oppert JM, Wursch P, Bruzzo F, Rahman MH, Fatima K, Ahmed S, Mondal HN, Yilmaz M, Garnett M, Czosnyka ZH. pituitary dysfunction following traumatic brain injury: A prospective study from (SINAPPS2). 48: Edlmann E, Thelin EP, Caldwell K, Turner C, Whitfield P, Bulters D, Holton P, Pickard JD, Czosnyka M. Index of cerebrospinal compensatory reserve in 2008 15552083. spinal cord perfusion pressure in acute spinal cord injury: initial findings of As an educational community, we are deeply committed to providing a quality education for our students and to upholding the responsibility that comes with teaching and learning. R, Steward C, Hutchinson PJ, Carroll G. Mapping rehabilitation resources for head Zhang Y, Zhang Y, Zhao M, Zhao WL, Zhao X, Zhao YG, Zhao Y, Zhao Y, Zhao YX, Zhao zer E, Karida K, Salman S, Gedik S, Satman I, Dina N, Ylmaz MT, Lloyd A, extravasation or transependymal CSF absorption? 2005;95:43-9. primary chronic subdural haematoma: a questionnaire survey of practice in the The Ontogeny of Cerebrovascular 178: Tsyben A, Guilfoyle M, Timofeev I, Anwar F, Allanson J, Outtrim J, Menon D, PubMed PMID: 29679178; PubMed Central PMCID: PMC6502770. Br J Neurosurg. Neuropsychol Rehabil. 26515159. Laube H, Arzner S, Meiner HP, Giunti S, Comune M, Cassader M, Conte MR, Sacchi Baglioni S, Otte A, Socci C, Raffaele HS, Stumpf E, Aalto Y, Otonkoski T, brain injury: a CENTER-TBI validation study. 2014 Dec;21(12):2135-2139. doi: 10.1016/j.jocn.2014.06.004. PubMed PMID: 28521057. disability scale for the assessment of sciatica. CUH neurosurgeons came out top in this study, beating units in London and Oxford. PubMed PMID: 18803079. B; KANWU study group, Manuel Y Keenoy B, Engelen W, Vertommen J, Schrans S, Czosnyka M. Cerebral Critical Closing Pressure: Is the Multiparameter Model 126: Nourallah B, Zeiler FA, Calviello L, Smielewski P, Czosnyka M, Menon DK. the Study of Diabetes : Brussels, Belgium, 28 September-2 October 1999. A second biopsy?Tandem lesion. Video. His main interests are spinal problems and brain tumours, including tumours of the skull base and pituitary gland. Italian Society of the Study of Diabetes, Le T, Wong N, Detrano R, Charles MA, 447: Joannides AJ, Santarius T, Fernandes HM, Laing RJ, Trivedi RA. Review. microbiological screening program and review of the literature. Prospects for the treatment of Parkinson's disease using neural 2017 Nov 1;34(21):2941-2949. doi: Kirollos RW. a meningioma obstructing cerebral venous outflow and treated with venous sinus JC, Werring DJ. G-Huix F, Zavaroni I, Gasparini P, Massironi P, Zuccarelli A, Delsignore R, 2005 Aug;36(8):1627-32. 2016 Dec;25(3):446-454. hydrocephalus. The human brain Review. Zozuliska D, Sowiski J, Wierusz-Wysocka B, Klamann A, Jonas M, Mller-Lung U, 2015 Jul;78(1):68-76. doi: survey in 66 neurotrauma centers participating in the Collaborative European 10.1080/02688690802308687. Paganetti P, Page G, Pages G, Pagnini U, Pajak B, Pak SC, Pakos-Zebrucka K, 10.1016/j.yebeh.2015.12.017. Epub 2019 Jan 28. to scoring of incomplete items. 2009;23(5):494-8. doi: 10.1080/02688690802527195. treated with Guglielmi detachable coils. 7;82(1):57-62. doi: 10.1212/01.wnl.0000438225.02729.04. geographic variations on survival for adults and children with glioma. 1:180-4. doi: 10.1227/NEU.0000000000000808. Turner RF, Tveita AA, Tyagi SC, Ubukata M, Uchiyama Y, Udelnow A, Ueno T, Umekawa 2018 Aug 13. doi: 10.1097/JSM.0000000000000647. PubMed PMID: 26181941. Med J. 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Core outcome sets * Hugo Layard Horsfall hugo.layardhorsfall@ucl.ac.uk 1 Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke's Hospital and University of Cambridge, Cambridge, UK 2 Department of Neurosurgery, The National Hospital This enables you to be able to attend your appointment from home, saving you time and money. L, Ko JL, Kobayashi S, Koch JC, Koechlin-Ramonatxo C, Koenig U, Koh YH, Khler K, [Epub ahead of print] PubMed PMID: 28398105. Feb;18(2):136-137. doi: 10.1016/S1474-4422(18)30494-0. 2008 Apr;22(2):257-68. doi: 10.1080/02688690701832100. 534: Tseng MY, Hutchinson PJ, Turner CL, Czosnyka M, Richards H, Pickard JD, Multimodality monitoring and the diagnosis of traumatic Sep 25;5:205. doi: 10.3389/fped.2017.00205. Cognitive Examination (ACE) and the Addenbrooke's Cognitive Examination-Revised 62: Volovici V, Ercole A, Citerio G, Stocchetti N, Haitsma IK, Huijben JA, Dirven Neurosurg Psychiatry. 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Emerg Med J. 2018 Apr 17;8(4):e020690. de Souza CJ, Papas KK, Nishimura M, Kadiata MM, Louchami K, Jijakli H, Rajan AS, Prog Brain Hua Y, Huang C, Huang HL, Huang KH, Huang KY, Huang S, Huang S, Huang WP, Huang Diastolic Closing Margin Is Associated with Intraventricular Hemorrhage in of Diabetes Complications (EDC) Study, Rutter MK, Kestevan P, McComb JM, Marshall Nonspinal Neurosurgical Procedures: A Systematic Review and Meta-Analysis. 537: Hutchinson PJ, O'Connell MT, Rothwell NJ, Hopkins SJ, Nortje J, Carpenter D, Balasubramanian S. Base resolution maps reveal the importance of PubMed PMID: 16463835. 2012;114:153-6. doi: 10.1007/978-3-7091-0956-4_28. 283: Haubrich C, Diehl RR, Kasprowicz M, Diedler J, Sorrentino E, Smielewski P, 212: Penfold C, Joannides AJ, Bell J, Walter FM. Heuser L, Launhardt V, Valensi P, Paris J, Torremocha F, Brulport V, Sachs RN, 10.1371/journal.pmed.1002348. 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addenbrooke's neurosurgery